Monosaccharides:
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Monosaccharides, also knows as simple
sugars are the monobasic units of carbohydrates. They cannot be further
hydrolysed to simpler chemical compounds. Monosaccharides have their empirical
formula of (C6H12O6). They are colourless
water-soluble, crystalline, sweet tested compounds.
Some of the examples of monosaccharides
are the Glucose, Fructose & Galactose. Each carbon atom
that supports a hydroxyl group is chiral, giving rise to a number of isomeric forms,
all with the same chemical formula. For instance, galactose and glucose are
both aldohexoses,
but have different physical structures and chemical properties.
Structure of monosaccharides: -
Monosaccharides having a chemical formula
of CmH2nOm. Monosaccharides can be determined
by the “Carbon atom count” of a compound. Depending on the number of carbon
atoms the monosaccharide compound can be named as triose (3), tetrose (4),
pentose (5), hexose (6), heptose (7) and so on. But a certain exception lies
where the empirical formula is not same for some of the monosaccharide compound
such as the deoxyribose sugar moiety. Monosaccharides with more than eight
carbon atoms are rare due to their instability in structural formation.
Monosaccharides in aqueous solution exist as ring structures if they have more
than four carbon atoms.
Two monosaccharide compounds have same
structural configuration and arrangements can still be distinguished by their stereoisomers,
which differ by the three-dimensional arrangements of their chemical bonds
between compounds.
For the determination Fischer projection
method is in best use to determine their differences by drawing a skeletal
structure of an acyclic monosaccharide so that the handedness of each chiral
carbon is well specified. Each stereoisomer of a simple open-chain
monosaccharide can be identified by the positions (right or left) in the
Fischer diagram of the chiral hydroxyls (the hydroxyls attached to the chiral
carbons).
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